Replication of H9 influenza viruses in the human ex vivo respiratory tract, and the influence of neuraminidase on virus release

Abstract H9N2 viruses are the most widespread influenza viruses in poultry in Asia. We evaluated the infection and tropism of human and avian H9 influenza virus in the human respiratory tract using ex vivo respiratory organ culture. H9 viruses infected the upper and lower respiratory tract and the m...

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Bibliographic Details
Main Authors: Renee W. Y. Chan, Louisa L. Y. Chan, Chris K. P. Mok, Jimmy Lai, Kin P. Tao, Adebimpe Obadan, Michael C. W. Chan, Daniel R. Perez, J. S. Malik Peiris, John M. Nicholls
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05853-5