The extracellular matrix protein Edil3 stimulates osteoblast differentiation through the integrin α5β1/ERK/Runx2 pathway.

The extracellular matrix protein Edil3 stimulates osteoblast differentiation through the integrin α5β1/ERK/Runx2 pathway.

Epidermal growth factor-like repeats and discoidin I-like domain 3 (Edil3) is an extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif that binds integrin. Recently, Edil3 has been implicated in various biological processes, including angiogenesis and cellular differentiation. It can in...

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Bibliographic Details
Main Authors: Sin-Hye Oh, Jung-Woo Kim, Yuri Kim, Mi Nam Lee, Min-Suk Kook, Eun Young Choi, Suhn-Young Im, Jeong-Tae Koh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5705136?pdf=render

Internet

http://europepmc.org/articles/PMC5705136?pdf=render

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