Traumatic brain injury is associated with increased syndecan-1 shedding in severely injured patients

Traumatic brain injury is associated with increased syndecan-1 shedding in severely injured patients

Abstract Introduction Head injury and exsanguination are the leading causes of death in trauma patients. Hemorrhagic shock triggers systemic endothelial glycocalyx breakdown, potentially leading to traumatic endotheliopathy (EoT). Levels of syndecan-1, a main glycocalyx component, have been used to...

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Bibliographic Details
Main Authors: Erika Gonzalez Rodriguez, Jessica C. Cardenas, Charles S. Cox, Ryan S. Kitagawa, Jakob Stensballe, John B. Holcomb, Pär I. Johansson, Charles E. Wade
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Subjects:
Endothelium
Syndecan-1
Traumatic endotheliopathy
Sympathoadrenal activation
Online Access:http://link.springer.com/article/10.1186/s13049-018-0565-3

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http://link.springer.com/article/10.1186/s13049-018-0565-3

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