DHAV-1 Inhibits Type I Interferon Signaling to Assist Viral Adaption by Increasing the Expression of SOCS3

DHAV-1 Inhibits Type I Interferon Signaling to Assist Viral Adaption by Increasing the Expression of SOCS3

Duck hepatitis A virus type 1 (DHAV-1) is one of the most lethal pathogens in the duck industry. The attenuated vaccine (the CH60 strain) is cultivated through serial passage in chicken embryos and is widely used for the prevention and control of the disease. However, the specific mechanism underlyi...

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Bibliographic Details
Main Authors: Jinyan Xie, Mingshu Wang, Anchun Cheng, Xin-Xin Zhao, Mafeng Liu, Dekang Zhu, Shun Chen, Renyong Jia, Qiao Yang, Ying Wu, Shaqiu Zhang, Yunya Liu, Yanling Yu, Ling Zhang, Xiaoyue Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
DHAV-1
IFNs
SOCS3
STATs
MX1
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00731/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00731/full

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