Alternative Pathway Involvement in Protoporphyria Patients Related to Sun Exposure

Alternative Pathway Involvement in Protoporphyria Patients Related to Sun Exposure

The homeostasis of tissues in a chronic disease is an essential function of the alternative pathway (AP) of the complement system (CS). However, if not controlled, it may also be detrimental to healthy cells with a consequent aggravation of symptoms. The protoporphyria (PP) is a rare chronic disease...

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Bibliographic Details
Main Authors: Francesca Granata, Lorena Duca, Valentina Brancaleoni, Silvia Fustinoni, Giacomo De Luca, Irene Motta, Giovanna Graziadei, Elena Di Pierro
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
protoporphyria
complement system
alternative pathway
phototoxic reaction
global radiation
UV detection
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.615620/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.615620/full

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