Disruption of CTCF at the miR-125b1 locus in gynecological cancers

<p>Abstract</p> <p>Background</p> <p>In cancer cells, transcriptional gene silencing has been associated with genetic and epigenetic defects. The disruption of DNA methylation patterns and covalent histone marks has been associated with cancer development. Until recentl...

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Main Authors: Soto-Reyes Ernesto, González-Barrios Rodrigo, Cisneros-Soberanis Fernanda, Herrera-Goepfert Roberto, Pérez Víctor, Cantú David, Prada Diddier, Castro Clementina, Recillas-Targa Félix, Herrera Luis A
Format: Article
Language:English
Published: BMC 2012-01-01
Series:BMC Cancer
Subjects:
Online Access:http://www.biomedcentral.com/1471-2407/12/40