Downregulation of epithelial sodium channel (ENaC) activity in human airway epithelia after low temperature incubation
Introduction The incubation of airway epithelia cells at low temperatures is a common in vitro experimental approach used in the field of cystic fibrosis (CF) research to thermo-stabilise F508del-CFTR and increase its functional expression. Given that the airway epithelium includes numerous ion tran...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2021-08-01
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Series: | BMJ Open Respiratory Research |
Online Access: | https://bmjopenrespres.bmj.com/content/8/1/e000861.full |