Downregulation of epithelial sodium channel (ENaC) activity in human airway epithelia after low temperature incubation

Introduction The incubation of airway epithelia cells at low temperatures is a common in vitro experimental approach used in the field of cystic fibrosis (CF) research to thermo-stabilise F508del-CFTR and increase its functional expression. Given that the airway epithelium includes numerous ion tran...

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Bibliographic Details
Main Authors: Sangya Yadav, Ciaran A Shaughnessy, Pamela L Zeitlin, Preston E Bratcher
Format: Article
Language:English
Published: BMJ Publishing Group 2021-08-01
Series:BMJ Open Respiratory Research
Online Access:https://bmjopenrespres.bmj.com/content/8/1/e000861.full