DNA methylation holds prognostic information in relapsed precursor B-cell acute lymphoblastic leukemia

DNA methylation holds prognostic information in relapsed precursor B-cell acute lymphoblastic leukemia

Abstract Background Few biological markers are associated with survival after relapse of B-cell precursor acute lymphoblastic leukemia (BCP-ALL). In pediatric T-cell ALL, we have identified promoter-associated methylation alterations that correlate with prognosis. Here, the prognostic relevance of C...

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Bibliographic Details
Main Authors: Magnus Borssén, Jessica Nordlund, Zahra Haider, Mattias Landfors, Pär Larsson, Jukka Kanerva, Kjeld Schmiegelow, Trond Flaegstad, Ólafur Gísli Jónsson, Britt-Marie Frost, Josefine Palle, Erik Forestier, Mats Heyman, Magnus Hultdin, Gudmar Lönnerholm, Sofie Degerman
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Clinical Epigenetics
Subjects:
DNA methylation
BCP-ALL
Prognosis
CIMP
Relapse
Risk stratification
Online Access:http://link.springer.com/article/10.1186/s13148-018-0466-3

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http://link.springer.com/article/10.1186/s13148-018-0466-3

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