Why Ablation of Sites With Purkinje Activation Is Antiarrhythmic: The Interplay Between Fast Activation and Arrhythmogenesis

Ablation of sites showing Purkinje activity is antiarrhythmic in some patients with idiopathic ventricular fibrillation (iVF). The mechanism for the therapeutic success of ablation is not fully understood. We propose that deeper penetrance of the Purkinje network allows faster activation of the vent...

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Bibliographic Details
Main Authors: Ruben Coronel, Mark Potse, Michel Haïssaguerre, Nicolas Derval, Mathilde R. Rivaud, Veronique M. F. Meijborg, Matthijs Cluitmans, Mélèze Hocini, Bastiaan J. Boukens
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.648396/full