Age-dependent astroglial vulnerability to hypoxia and glutamate: the role for erythropoietin.

Extracellular accumulation of toxic concentrations of glutamate (Glu) is a hallmark of many neurodegenerative diseases, often accompanied by hypoxia and impaired metabolism of this neuromediator. To address the question whether the multifunctional neuroprotective action of erythropoietin (EPO) exten...

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Bibliographic Details
Main Authors: Ali Lourhmati, Gayane H Buniatian, Christina Paul, Stephan Verleysdonk, Reinhild Buecheler, Marine Buadze, Barbara Proksch, Matthias Schwab, Christoph H Gleiter, Lusine Danielyan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3790708?pdf=render