A reliable method for the selection of exploitable melanoma archival paraffin embedded tissues for transcript biomarker profiling.

The source tissue for biomarkers mRNA expression profiling of tumors has traditionally been fresh-frozen tissue. The adaptation of formalin-fixed, paraffin-embedded (FFPE) tissues for routine mRNA profiling would however be invaluable in view of their abundance and the clinical information related t...

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Bibliographic Details
Main Authors: Celeste Lebbe, Mickael Guedj, Nicole Basset-Seguin, Marie Pierre Podgorniak, Suzanne Menashi, Anne Janin, Samia Mourah
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3260139?pdf=render