Independent and joint correlation of PNPLA3 I148M and TM6SF2 E167K variants with the risk of coronary heart disease in patients with non-alcoholic fatty liver disease

Independent and joint correlation of PNPLA3 I148M and TM6SF2 E167K variants with the risk of coronary heart disease in patients with non-alcoholic fatty liver disease

Abstract Background CHD is reported to be the primary cause of death in patients with NAFLD. Genetic susceptibility genes contribute to the developmental risk of NAFLD or CHD. Whether the genetic factors could affect the risk of CHD in NAFLD patients is not clear. The aim of this study was to invest...

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Bibliographic Details
Main Authors: Jian-Ting Wu, Shou-Sheng Liu, Xiang-Jun Xie, Qun Liu, Yong-Ning Xin, Shi-Ying Xuan
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Lipids in Health and Disease
Subjects:
PNPLA3 I148M
TM6SF2 E167K
Non-alcoholic fatty liver disease
Coronary heart disease
Online Access:http://link.springer.com/article/10.1186/s12944-020-01207-9

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http://link.springer.com/article/10.1186/s12944-020-01207-9

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