HIV-1 Tat stimulates transcription complex assembly through recruitment of TBP in the absence of TAFs.
The human immunodeficiency virus type I (HIV-1) transactivator protein Tat is an unusual transcriptional activator that is thought to act solely by promoting RNA polymerase II processivity. Here we study the mechanism of Tat action by analyzing transcription complex (TC) assembly in vivo using chrom...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2005-02-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC546330?pdf=render |