Dapagliflozin acutely improves endothelial dysfunction, reduces aortic stiffness and renal resistive index in type 2 diabetic patients: a pilot study

Dapagliflozin acutely improves endothelial dysfunction, reduces aortic stiffness and renal resistive index in type 2 diabetic patients: a pilot study

Abstract Background Sodium-glucose cotransporter-2 inhibitors reduce blood pressure (BP) and renal and cardiovascular events in patients with type 2 diabetes through not fully elucidated mechanisms. Aim of this study was to investigate whether dapagliflozin is able to acutely modify systemic and ren...

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Bibliographic Details
Main Authors: Anna Solini, Livia Giannini, Marta Seghieri, Edoardo Vitolo, Stefano Taddei, Lorenzo Ghiadoni, Rosa Maria Bruno
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Cardiovascular Diabetology
Subjects:
Dapagliflozin
SGLT2-inhibitors
Thiazide diuretics
Endothelium
Flow-mediated dilation
Pulse wave velocity
Online Access:http://link.springer.com/article/10.1186/s12933-017-0621-8

Internet

http://link.springer.com/article/10.1186/s12933-017-0621-8

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