OncomiR addiction is generated by a miR-155 feedback loop in Theileria-transformed leukocytes.

The intracellular parasite Theileria is the only eukaryote known to transform its mammalian host cells. We investigated the host mechanisms involved in parasite-induced transformation phenotypes. Tumour progression is a multistep process, yet 'oncogene addiction' implies that cancer cell g...

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Bibliographic Details
Main Authors: Justine Marsolier, Sandra Pineau, Souhila Medjkane, Martine Perichon, Qinyan Yin, Erik Flemington, Matthew D Weitzman, Jonathan B Weitzman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3630095?pdf=render