Tumor Microenvironment: Extracellular Matrix Alterations Influence Tumor Progression

Tumor Microenvironment: Extracellular Matrix Alterations Influence Tumor Progression

The tumor microenvironment (TME) is composed of various cell types embedded in an altered extracellular matrix (ECM). ECM not only serves as a support for tumor cell but also regulates cell–cell or cell–matrix cross-talks. Alterations in ECM may be induced by hypoxia and acidosis, by oxygen free rad...

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Bibliographic Details
Main Authors: Sylvie Brassart-Pasco, Stéphane Brézillon, Bertrand Brassart, Laurent Ramont, Jean-Baptiste Oudart, Jean Claude Monboisse
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Oncology
Subjects:
cancer
microenvironment
extracellular matrix
matrikines
integrins
proteases
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00397/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.00397/full

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