Role of enterocyte stearoyl-Co-A desaturase-1 in LDLR-null mice

Role of enterocyte stearoyl-Co-A desaturase-1 in LDLR-null mice

After crossing floxed stearoyl-CoA desaturase-1 (Scd1fl/fl) mice with LDL receptor-null (ldlr−/−) mice, and then Villin Cre (VilCre) mice, enterocyte Scd1 expression in Scd1fl/fl/ldlr−/−/VilCre mice was reduced 70%. On Western diet (WD), Scd1fl/fl/ldlr−/− mice gained more weight than Scd1fl/fl/ldlr−...

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Bibliographic Details
Main Authors: Pallavi Mukherjee, Greg Hough, Arnab Chattopadhyay, Victor Grijalva, Ellen Ines O'Connor, David Meriwether, Alan Wagner, James M. Ntambi, Mohamad Navab, Srinivasa T. Reddy, Alan M. Fogelman
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Journal of Lipid Research
Subjects:
atherosclerosis
apolipoprotein A-I mimetic peptides
Tg6F
lipopolysaccharide-binding protein
cluster of differentiation 14
toll-like receptor 4
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520341754

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http://www.sciencedirect.com/science/article/pii/S0022227520341754

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