Biochemical and functional analysis of Drosophila-sciara chimeric sex-lethal proteins.

The Drosophila SXL protein controls sex determination and dosage compensation. It is a sex-specific factor controlling splicing of its own Sxl pre-mRNA (auto-regulation), tra pre-mRNA (sex determination) and msl-2 pre-mRNA plus translation of msl-2 mRNA (dosage compensation). Outside the drosophilid...

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Bibliographic Details
Main Authors: María Fernanda Ruiz, Francesca Sarno, Silvia Zorrilla, Germán Rivas, Lucas Sánchez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3677924?pdf=render