The N terminus of orf virus-encoded protein 002 inhibits acetylation of NF-κB p65 by preventing Ser(276) phosphorylation.

The N terminus of orf virus-encoded protein 002 inhibits acetylation of NF-κB p65 by preventing Ser(276) phosphorylation.

Orf virus-encoded protein 002 (ORFV002) inhibits NF-κB signaling pathway by decreasing the acetylation of NF-κB-p65 through interference of NF-κB p65's association with NF-κB p300. However, the precise mechanism of how ORFV002 interferes with the NF-κB p65/p300 association is still unknown. Due...

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Bibliographic Details
Main Authors: Zhangyong Ning, Zewei Zheng, Wenbo Hao, Chaohui Duan, Wei Li, Yuanyuan Wang, Ming Li, Shuhong Luo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23536830/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23536830/?tool=EBI

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