A Continuous Battle for Host-Derived Glycans Between a Mucus Specialist and a Glycan Generalist in vitro and in vivo

A Continuous Battle for Host-Derived Glycans Between a Mucus Specialist and a Glycan Generalist in vitro and in vivo

The human gastrointestinal tract is colonized by a diverse microbial community, which plays a crucial role in human health. In the gut, a protective mucus layer that consists of glycan structures separates the bacteria from the host epithelial cells. These host-derived glycans are utilized by bacter...

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Bibliographic Details
Main Authors: Ioannis Kostopoulos, Steven Aalvink, Petia Kovatcheva-Datchary, Bart Nijsse, Fredrik Bäckhed, Jan Knol, Willem M. de Vos, Clara Belzer
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Microbiology
Subjects:
Akkermansia muciniphila
Bacteroides thetaiotaomicron
mucin glycans
glycosyl hydrolases
antimicrobial proteins
germ free mice
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.632454/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.632454/full

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