Effect of nitazoxanide on albendazole pharmacokinetics in cerebrospinal fluid and plasma in rats

Background: Although albendazole is the drug-of-choice for the treatment of neurocysticercosis, its efficacy is limited due to its low bioavailability. An alternative for optimizing pharmacological treatment is through drug combinations. In vitro studies have shown that nitazoxanide and tizoxanide (...

Full description

Bibliographic Details
Main Authors: María Isabel Ruiz-Olmedo, Iliana González-Hernández, Francisca Palomares-Alonso, Javier Franco-Pérez, María de Lourdes González F., Helgi Jung-Cook
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Saudi Pharmaceutical Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016416300974