Influence of Ecto-nucleoside triphosphate diphosphohydrolase activity on Trypanosoma cruzi infectivity and virulence.

BACKGROUND: The protozoan Trypanosoma cruzi is the causative agent of Chagas disease. There are no vaccines or effective treatment, especially in the chronic phase when most patients are diagnosed. There is a clear necessity to develop new drugs and strategies for the control and treatment of Chagas...

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Main Authors: Ramon F Santos, Marcela A S Pôssa, Matheus S Bastos, Paulo M M Guedes, Márcia R Almeida, Ricardo Demarco, Sergio Verjovski-Almeida, Maria T Bahia, Juliana L R Fietto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2644763?pdf=render