Vitamin D Receptor Gene Polymorphisms Are Associated With Leprosy in Southern Brazil

Vitamin D Receptor Gene Polymorphisms Are Associated With Leprosy in Southern Brazil

Vitamin D, together with its nuclear receptor (VDR), plays an important role in modulating the immune response, decreasing the inflammatory process. Some polymorphisms of the VDR gene, such as BsmI (G>A rs1544410), ApaI (G>T rs7975232), and TaqI (T>C rs731236) could affect its s...

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Bibliographic Details
Main Authors: Afonso Carrasco Pepineli, Hugo Vicentin Alves, Bruna Tiaki Tiyo, Luciana Conci Macedo, Lorena Visentainer, Quirino Alves de Lima Neto, Joana Maira Valentini Zacarias, Ana Maria Sell, Jeane Eliete Laguila Visentainer
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
multibacillary
paucibacillary
genetic polymorphism
case-control studies
gene frequencies
biological markers
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02157/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02157/full

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