Protective role of Lactobacillus plantarum A7 against irinotecan-induced genotoxicity

Objective: Irinotecan is a botanical derivative and an anti-cancer drug with cytotoxic and genotoxic effects. The present study evaluated the effect of Lactobacillus plantarum A7 on the genotoxic activity of irinotecan in a hepatocellular carcinoma cell line (HepG2) by comet assay. Materials and Met...

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Bibliographic Details
Main Authors: Soheila Sepahi, Abbas Jafarian-Dehkordi, Maryam Mirlohi, kobra shirani, Mahmoud Etebari
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2016-04-01
Series:Avicenna Journal of Phytomedicine
Subjects:
Online Access:http://ajp.mums.ac.ir/article_5962_f3d10d3d831ba187f1f82268f4e3a7fd.pdf