IFN-β-inducing, unusual viral RNA species produced by paramyxovirus infection accumulated into distinct cytoplasmic structures in an RNA-type-dependent manner

The interferon (IFN) system is one of the most important defensive responses of mammals against viruses, and is rapidly evoked when the pathogen-associated molecular patterns (PAMPs) of viruses are sensed. Non-self, virus-derived RNA species have been identified as the PAMPs of RNA viruses. In the p...

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Bibliographic Details
Main Authors: Asuka eYoshida, Ryoko eKawabata, Tomoyuki eHonda, Keizo eTomonaga, Takemasa eSakaguchi, Takashi eIrie
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00804/full