Comparison of Immunohistochemistry and Direct Sanger Sequencing for Detection of the Mutation in Thyroid Neoplasm

Comparison of Immunohistochemistry and Direct Sanger Sequencing for Detection of the Mutation in Thyroid Neoplasm

BackgroundThe BRAFV600E mutation is the most common genetic alteration identified in papillary thyroid carcinoma (PTC). Because of its costs effectiveness and sensitivity, direct Sanger sequencing has several limitations. The aim of this study was to evaluate the efficiency of immunohistochemistry (...

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Bibliographic Details
Main Authors: Hye-Seon Oh, Hyemi Kwon, Suyeon Park, Mijin Kim, Min Ji Jeon, Tae Yong Kim, Young Kee Shong, Won Bae Kim, Jene Choi, Won Gu Kim, Dong Eun Song
Format: Article
Language:English
Published: Academya Publishing Co. 2018-01-01
Series:Endocrinology and Metabolism
Subjects:
Immunohistochemistry
Sanger sequencing
BRAF
Mutation
Thyroid neoplasms
Online Access:https://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-33-62.pdf

Internet

https://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-33-62.pdf

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