MALVA: Genotyping by Mapping-free ALlele Detection of Known VAriants

Summary: The amount of genetic variation discovered in human populations is growing rapidly leading to challenging computational tasks, such as variant calling. Standard methods for addressing this problem include read mapping, a computationally expensive procedure; thus, mapping-free tools have bee...

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Bibliographic Details
Main Authors: Luca Denti, Marco Previtali, Giulia Bernardini, Alexander Schönhuth, Paola Bonizzoni
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219302366