A genetic approach to the recruitment of PRC2 at the HoxD locus.

A genetic approach to the recruitment of PRC2 at the HoxD locus.

Polycomb group (PcG) proteins are essential for the repression of key factors during early development. In Drosophila, the polycomb repressive complexes (PRC) associate with defined polycomb response DNA elements (PREs). In mammals, however, the mechanisms underlying polycomb recruitment at targeted...

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Bibliographic Details
Main Authors: Patrick Schorderet, Nicolas Lonfat, Fabrice Darbellay, Patrick Tschopp, Sandra Gitto, Natalia Soshnikova, Denis Duboule
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3820793?pdf=render

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http://europepmc.org/articles/PMC3820793?pdf=render

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