Germline EPHB2 receptor variants in familial colorectal cancer.

Familial clustering of colorectal cancer occurs in 15-20% of cases, however recognized cancer syndromes explain only a small fraction of this disease. Thus, the genetic basis for the majority of hereditary colorectal cancer remains unknown. EPHB2 has recently been implicated as a candidate tumor sup...

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Bibliographic Details
Main Authors: George Zogopoulos, Claus Jorgensen, Julinor Bacani, Alexandre Montpetit, Pierre Lepage, Vincent Ferretti, Lauren Chad, Subani Selvarajah, Brent Zanke, Thomas J Hudson, Tony Pawson, Steven Gallinger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2483346?pdf=render