P-MAPA immunotherapy potentiates the effect of cisplatin on serous ovarian carcinoma through targeting TLR4 signaling

P-MAPA immunotherapy potentiates the effect of cisplatin on serous ovarian carcinoma through targeting TLR4 signaling

Abstract Background Toll-like receptors (TLRs) are transmembrane proteins expressed on the surface of ovarian cancer (OC) and immune cells. Identifying the specific roles of the TLR-mediated signaling pathways in OC cells is important to guide new treatments. Because immunotherapies have emerged as...

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Bibliographic Details
Main Authors: Luiz Gustavo de Almeida Chuffa, Grazielle de Moura Ferreira, Luiz Antonio Lupi, Iseu da Silva Nunes, Wagner José Fávaro
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Journal of Ovarian Research
Subjects:
Ovarian cancer
P-MAPA
Cisplatin
TLR2
TLR4
NF-kB
Online Access:http://link.springer.com/article/10.1186/s13048-018-0380-5

Internet

http://link.springer.com/article/10.1186/s13048-018-0380-5

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