Quantitating morphological changes in biological samples during scanning electron microscopy sample preparation with correlative super-resolution microscopy.

Quantitating morphological changes in biological samples during scanning electron microscopy sample preparation with correlative super-resolution microscopy.

Sample preparation is critical to biological electron microscopy (EM), and there have been continuous efforts on optimizing the procedures to best preserve structures of interest in the sample. However, a quantitative characterization of the morphological changes associated with each step in EM samp...

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Bibliographic Details
Main Authors: Ying Zhang, Tao Huang, Danielle M Jorgens, Andrew Nickerson, Li-Jung Lin, Joshua Pelz, Joe W Gray, Claudia S López, Xiaolin Nan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5451012?pdf=render

Internet

http://europepmc.org/articles/PMC5451012?pdf=render

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