Endoplasmic Reticulum Stress (ER Stress) and Unfolded Protein Response (UPR) Occur in a Rat Varicocele Testis Model

Endoplasmic Reticulum Stress (ER Stress) and Unfolded Protein Response (UPR) Occur in a Rat Varicocele Testis Model

Using a surgically induced varicocele rat model, we show here strong evidence that the misfolded/unfolded protein response that is part of the stress response of the endoplasmic reticulum (ER) is activated in the varicocele testis (VCL), leading to the induction of apoptosis. To support this hypothe...

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Bibliographic Details
Main Authors: Mahshid Hosseini, Erfaneh Shaygannia, Mohsen Rahmani, Anahita Eskandari, Aram Ahmadzadeh Golsefid, Marziyeh Tavalaee, Parviz Gharagozloo, Joël R. Drevet, Mohammad H. Nasr-Esfahani
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2020/5909306

Internet

http://dx.doi.org/10.1155/2020/5909306

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