Akkermansia muciniphila-Derived Extracellular Vesicles as a Mucosal Delivery Vector for Amelioration of Obesity in Mice

Akkermansia muciniphila-Derived Extracellular Vesicles as a Mucosal Delivery Vector for Amelioration of Obesity in Mice

Recent evidence suggests that probiotics can restore the mucosal barrier integrity, ameliorate inflammation, and promote homeostasis required for metabolism in obesity by affecting the gut microbiota composition. In this study, we investigated the effect of Akkermansia muciniphila and its extracellu...

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Bibliographic Details
Main Authors: Fatemeh Ashrafian, Arefeh Shahriary, Ava Behrouzi, Hamid Reza Moradi, Shahrbanoo Keshavarz Azizi Raftar, Arezou Lari, Shima Hadifar, Rezvan Yaghoubfar, Sara Ahmadi Badi, Shohre Khatami, Farzam Vaziri, Seyed Davar Siadat
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Microbiology
Subjects:
gut microbiota
Akkermansia muciniphila
extracellular vesicles
toll-like receptors
tight junction
peroxisome proliferator-activated receptors
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02155/full

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https://www.frontiersin.org/article/10.3389/fmicb.2019.02155/full

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