A detrimental role of RelB in mature oligodendrocytes during experimental acute encephalomyelitis

A detrimental role of RelB in mature oligodendrocytes during experimental acute encephalomyelitis

Abstract Background Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS). It is firmly established that overactivation of the p65 (RelA) nuclear factor kappa B (NF-κB) transcription factor upregulates expression of inflammatory mediators in both immune a...

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Bibliographic Details
Main Authors: Angela S. Gupta, Debolina D. Biswas, La Shardai N. Brown, Karli Mockenhaupt, Michael Marone, Andrew Hoskins, Ulrich Siebenlist, Tomasz Kordula
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Journal of Neuroinflammation
Subjects:
EAE
Inflammation
RelB
Oligodendrocytes
Astrocytes
NF-κB
Online Access:http://link.springer.com/article/10.1186/s12974-019-1548-7

Internet

http://link.springer.com/article/10.1186/s12974-019-1548-7

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