Galectin-3 Regulates Atrial Fibrillation Remodeling and Predicts Catheter Ablation Outcomes

Galectin-3 Regulates Atrial Fibrillation Remodeling and Predicts Catheter Ablation Outcomes

Atrial fibrillation (AF) usually starts as paroxysmal but can evolve relentlessly to the persistent and permanent forms. However, the mechanisms governing such a transition are unknown. The authors show that intracardiac serum levels of galectin (Gal)-3 are greater in patients with persistent than p...

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Main Authors: Yoshio Takemoto, MD, PhD, Rafael J. Ramirez, PhD, Miki Yokokawa, MD, Kuljeet Kaur, PhD, Daniela Ponce-Balbuena, PhD, Mohamad C. Sinno, MD, B. Cicero Willis, MD, Hamid Ghanbari, MD, Steven R. Ennis, PhD, Guadalupe Guerrero-Serna, PhD, Bettina C. Henzi, MD, Rakesh Latchamsetty, MD, Roberto Ramos-Mondragon, PhD, Hassan Musa, PhD, Raphael P. Martins, MD, Sandeep V. Pandit, PhD, Sami F. Noujaim, PhD, Thomas Crawford, MD, Krit Jongnarangsin, MD, Frank Pelosi, MD, Frank Bogun, MD, Aman Chugh, MD, Omer Berenfeld, PhD, Fred Morady, MD, Hakan Oral, MD, José Jalife, MD
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:JACC: Basic to Translational Science
Subjects:
atrial fibrillation
catheter ablation
fibrosis
galectin-3
upstream therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X16000383

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http://www.sciencedirect.com/science/article/pii/S2452302X16000383

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