Single‐cell characterization and metabolic profiling of in vitro cultured human skeletal progenitors with enhanced in vivo bone forming capacity

Abstract Cell populations and their interplay provide the basis of a cell‐based regenerative construct. Serum‐free preconditioning can overcome the less predictable behavior of serum expanded progenitor cells, but the underlying mechanism and how this is reflected in vivo remains unknown. Herein, th...

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Bibliographic Details
Main Authors: Johanna Bolander, Tim Herpelinck, Malay Chaklader, Charikleia Gklava, Liesbet Geris, Frank P. Luyten
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:Stem Cells Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/sctm.19-0151