Valproic acid-induced amphiregulin secretion confers resistance to temozolomide treatment in human glioma cells
Abstract Background Glioblastoma multiforme (GBM) is the most severe type of primary brain tumor with a high mortality rate. Although extensive treatments for GBM, including resection, irradiation, chemotherapy and immunotherapy, have been tried, the prognosis is still poor. Temozolomide (TMZ), an a...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-08-01
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| Series: | BMC Cancer |
| Online Access: | http://link.springer.com/article/10.1186/s12885-019-5843-6 |