GIGANTEA is a co-chaperone which facilitates maturation of ZEITLUPE in the Arabidopsis circadian clock

The plant-specific GIGANTEA protein regulates the circadian clock by stabilizing the F-box protein ZEITLUPE via an unknown mechanism. Here Cha et al. show that GIGANTEA has intrinsic chaperone activity and can facilitate ZEITLUPE maturation by acting synergistically with HSP90.

Bibliographic Details
Main Authors: Joon-Yung Cha, Jeongsik Kim, Tae-Sung Kim, Qingning Zeng, Lei Wang, Sang Yeol Lee, Woe-Yeon Kim, David E. Somers
Format: Article
Language:English
Published: Nature Publishing Group 2017-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-016-0014-9