Secoisolariciresinol diglucoside is a blood-brain barrier protective and anti-inflammatory agent: implications for neuroinflammation

Abstract Background Secoisolariciresinol diglucoside (SDG), the main lignan in flaxseed, is known for its beneficial effects in inflammation, oxidative stress, heart disease, tumor progression, atherosclerosis, and diabetes. SDG might be an attractive natural compound that protects against neuroinfl...

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Bibliographic Details
Main Authors: Slava Rom, Viviana Zuluaga-Ramirez, Nancy L. Reichenbach, Michelle A. Erickson, Malika Winfield, Sachin Gajghate, Melpo Christofidou-Solomidou, Kelly L. Jordan-Sciutto, Yuri Persidsky
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Journal of Neuroinflammation
Online Access:http://link.springer.com/article/10.1186/s12974-018-1065-0