Local administration of AAV-BDNF to subventricular zone induces functional recovery in stroke rats.

Migration of new neuroprogenitor cells (NPCs) from the subventricular zone (SVZ) plays an important role in neurorepair after injury. Previous studies have shown that brain derived neurotrophic factor (BDNF) enhances the migration of NPCs from SVZ explants in neonatal mice in vitro. The purpose of t...

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Bibliographic Details
Main Authors: Seong-Jin Yu, Kuan-Yin Tseng, Hui Shen, Brandon K Harvey, Mikko Airavaara, Yun Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24312581/pdf/?tool=EBI