Assessment of interactions of efavirenz solid drug nanoparticles with human immunological and haematological systems

Assessment of interactions of efavirenz solid drug nanoparticles with human immunological and haematological systems

Abstract Background Recent work has developed solid drug nanoparticles (SDNs) of efavirenz that have been demonstrated, preclinically, improved oral bioavailability and the potential to enable up to a 50% dose reduction, and is currently being studied in a healthy volunteer clinical trial. Other SDN...

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Bibliographic Details
Main Authors: Neill J. Liptrott, Marco Giardiello, Tom O. McDonald, Steve P. Rannard, Andrew Owen
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Journal of Nanobiotechnology
Subjects:
HIV
Antiretroviral
Biocompatibility
Immunotoxicity
Haematotoxicity
Online Access:http://link.springer.com/article/10.1186/s12951-018-0349-y

Internet

http://link.springer.com/article/10.1186/s12951-018-0349-y

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