Assessment of interactions of efavirenz solid drug nanoparticles with human immunological and haematological systems
Abstract Background Recent work has developed solid drug nanoparticles (SDNs) of efavirenz that have been demonstrated, preclinically, improved oral bioavailability and the potential to enable up to a 50% dose reduction, and is currently being studied in a healthy volunteer clinical trial. Other SDN...
Main Authors: | Neill J. Liptrott, Marco Giardiello, Tom O. McDonald, Steve P. Rannard, Andrew Owen |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-03-01
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Series: | Journal of Nanobiotechnology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12951-018-0349-y |
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