Serial Monitoring of Circulating Tumor DNA in Patients With Metastatic Colorectal Cancer to Predict the Therapeutic Response

Serial Monitoring of Circulating Tumor DNA in Patients With Metastatic Colorectal Cancer to Predict the Therapeutic Response

Early biomarkers of therapeutic responses can help optimize the treatment of metastatic colorectal cancers (mCRC). In this prospective exploratory study, we examined serial changes of plasma-circulating tumor DNA (ctDNA) in 41 mCRC patients receiving first-line chemotherapies and tested its associat...

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Bibliographic Details
Main Authors: Ning Jia, Zhao Sun, Xin Gao, Yuejuan Cheng, Yanping Zhou, Chunying Shen, Wei Chen, Xueliang Wang, Rong Shi, Nan Li, Jianfeng Zhou, Chunmei Bai
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Genetics
Subjects:
liquid biopsy
circulating tumor DNA
metastatic colorectal cancer
therapeutic response
biomarker
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00470/full

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https://www.frontiersin.org/article/10.3389/fgene.2019.00470/full

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