Using the Drosophila Nephrocyte to Model Podocyte Function and Disease

Using the Drosophila Nephrocyte to Model Podocyte Function and Disease

Glomerular disorders are a major cause of end-stage renal disease and effective therapies are often lacking. Nephrocytes are considered to be part of the Drosophila excretory system and form slit diaphragms across cellular membrane invaginations. Nehphrocytes have been shown to share functional, mor...

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Bibliographic Details
Main Authors: Martin Helmstädter, Tobias B. Huber, Tobias Hermle
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Pediatrics
Subjects:
nephrocyte
Drosophila
podocyte
glomerular disease
garland cell
endocytosis
Online Access:http://journal.frontiersin.org/article/10.3389/fped.2017.00262/full

Internet

http://journal.frontiersin.org/article/10.3389/fped.2017.00262/full

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