Correlating genomic copy number alterations with clinicopathologic findings in 75 cases of hepatocellular carcinoma

Correlating genomic copy number alterations with clinicopathologic findings in 75 cases of hepatocellular carcinoma

Abstract Background Oligonucleotide array comparative genomic hybridization (aCGH) analysis has been used for detecting somatic copy number alterations (CNAs) in various types of tumors. This study aimed to assess the clinical utility of aCGH for cases of hepatocellular carcinoma (HCC) and to evalua...

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Bibliographic Details
Main Authors: Gang Peng, Hongyan Chai, Weizhen Ji, Yufei Lu, Shengming Wu, Hongyu Zhao, Peining Li, Qiping Hu
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Medical Genomics
Subjects:
Hepatocellular carcinoma (HCC)
Array comparative genomic hybridization (aCGH)
Copy number aberrations (CNAs)
Edmondson-Steiner (E-S) grading
Barcelona-Clinic Liver Cancer (BCLC) stages
Online Access:https://doi.org/10.1186/s12920-021-00998-9

Internet

https://doi.org/10.1186/s12920-021-00998-9

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