Systematic comparison of constitutive promoters and the doxycycline-inducible promoter.

Constitutive promoters are used routinely to drive ectopic gene expression. Here, we carried out a systematic comparison of eight commonly used constitutive promoters (SV40, CMV, UBC, EF1A, PGK and CAGG for mammalian systems, and COPIA and ACT5C for Drosophila systems). We also included in the compa...

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Bibliographic Details
Main Authors: Jane Yuxia Qin, Li Zhang, Kayla L Clift, Imge Hulur, Andy Peng Xiang, Bing-Zhong Ren, Bruce T Lahn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2868906?pdf=render