Comprehensive kinome NGS targeted expression profiling by KING-REX

Comprehensive kinome NGS targeted expression profiling by KING-REX

Abstract Background Protein kinases are enzymes controlling different cellular functions. Genetic alterations often result in kinase dysregulation, making kinases a very attractive class of druggable targets in several human diseases. Existing approved drugs still target a very limited portion of th...

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Bibliographic Details
Main Authors: Giovanni Carapezza, Carlo Cusi, Ettore Rizzo, Laura Raddrizzani, Sebastiano Di Bella, Alessio Somaschini, Antonella Leone, Rosita Lupi, Margherita Mutarelli, Vincenzo Nigro, Diego di Bernardo, Paolo Magni, Antonella Isacchi, Roberta Bosotti
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Genomics
Subjects:
Kinome gene expression
NGS RNA targeted panel
Online Access:http://link.springer.com/article/10.1186/s12864-019-5676-3

Internet

http://link.springer.com/article/10.1186/s12864-019-5676-3

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