Atypical Rho GTPases of the RhoBTB Subfamily: Roles in Vesicle Trafficking and Tumorigenesis

RhoBTB proteins constitute a subfamily of atypical Rho GTPases represented in mammals by RhoBTB1, RhoBTB2, and RhoBTB3. Their characteristic feature is a carboxyl terminal extension that harbors two BTB domains capable of assembling cullin 3-dependent ubiquitin ligase complexes. The expression of al...

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Bibliographic Details
Main Authors: Wei Ji, Francisco Rivero
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Cells
Subjects:
Online Access:http://www.mdpi.com/2073-4409/5/2/28