Interplay of Inflammatory Mediators with Epigenetics and Cartilage Modifications in Osteoarthritis

Osteoarthritis (OA), a degenerative disease of diarthrodial joints, is influenced by mechanical and inflammatory factors with aging, obesity, chronic injuries, and secondary diseases thought to be major factors driving the process of articular cartilage degeneration. Chondrocytes, the cellular compo...

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Bibliographic Details
Main Authors: Swarna Raman, Una FitzGerald, J. Mary Murphy
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fbioe.2018.00022/full