Methylseleninic acid sensitizes Notch3-activated OVCA429 ovarian cancer cells to carboplatin.

Ovarian cancer, the deadliest of gynecologic cancers, is usually not diagnosed until advanced stages. Although carboplatin has been popular for treating ovarian cancer for decades, patients eventually develop resistance to this platinum-containing drug. Expression of neurogenic locus notch homolog 3...

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Bibliographic Details
Main Authors: Tiffany J Tzeng, Lei Cao, YangXin Fu, Huawei Zeng, Wen-Hsing Cheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4092030?pdf=render